Ardelyx Q3 product revenue rises 19% to $125.5 million; 2026 guidance reaffirmed
Ardelyx reported third-quarter 2026 results on November 3, 2026, with total product revenue up 19% to $125.5 million and a net loss narrowing to $0.7 million from $1.0 million a year earlier. The company reiterated its full-year 2026 revenue and operating expense guidance and reported $285.3 million in cash, cash equivalents and short-term investments as of September 30, 2026. Research and development expenses rose 39% and SG&A expenses rose 12% year over year, and the company said the ACCEL Phase 3 trial in chronic idiopathic constipation is fully enrolled.
Key points
- Total product revenue of $125.5 million for the quarter ended September 30, 2026, versus $105.5 million a year earlier; IBSRELA $96.3 million (up 23%) and XPHOZAH $29.2 million (up 7%).
- Net loss of $0.7 million, or $(0.00) per share, versus a net loss of $1.0 million a year earlier; R&D expenses were $25.2 million and SG&A expenses were $93.9 million.
- Full-year 2026 guidance reiterated: IBSRELA revenue $350 million to $370 million, XPHOZAH revenue $110 million to $120 million, and operating expenses below $500 million.
- Cash and short-term investments of $285.3 million at September 30, 2026, up from $264.7 million at December 31, 2025; topline data from the ACCEL trial expected in the second half of 2027.
The filing
Written by AI on Nov 9, 2026, 10:08 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on November 03, 2026.
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