Perspective Therapeutics Reports Interim Melanoma Data: 2 of 8 Partial Responses
Perspective Therapeutics (CATX) filed an 8-K on November 6, 2026 with a press release and poster presenting updated interim results from its Phase 1/2a trial of [212Pb]lapemelanotide zapixetar (VMT01) in unresectable or metastatic melanoma, presented at the SITC 41st Annual Meeting in Phoenix. The filing reports antitumor activity at the 3.0 mCi dose and no dose-limiting toxicities across 20 patients, but the sample is small and the company says it is still evaluating dose optimization. The update is early-stage clinical data and contains no financial results or guidance.
Key points
- Data cover 20 patients in three monotherapy cohorts as of the September 18, 2026 data cutoff; no dose-limiting toxicities were reported
- At the 3.0 mCi dose, 2 of 8 patients had objective partial responses and the disease control rate was 75%
- Grade 3 or higher treatment-emergent adverse events occurred in 5 of 20 patients (25%), none considered treatment-related
The filing
Written by AI on Nov 9, 2026, 7:05 AM ET, from this filing only.
Briefs are written by AI from the filing text and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the AI's reading of the filing for shareholders, not a price forecast. Not investment advice.