Eikon Therapeutics presents EIK1003, EIK1004 and EIK1005 clinical data at ESMO Congress
Eikon Therapeutics presented updated and initial clinical data from its PARP1 and WRN helicase programs at the 2026 ESMO Congress on October 23, 2026, and issued a press release on the results. The filing reports objective response rates alongside frequent Grade 3 or higher adverse events, and it contains no financial results, so the effect on shareholders is mixed and depends on later development steps.
Key points
- EIK1003 Cohort 1C with weekly paclitaxel: objective response rate 26.4% (14/53); Grade 3 or higher adverse events in 80.3% (49/61) of participants
- EIK1003 monotherapy Cohort 1A: objective response rate 14.3% (7/49) among efficacy-evaluable participants, with data cutoff October 1, 2026
- EIK1004 monotherapy: objective response rate 12.1% (7/58); Grade 3 or higher adverse events in 17.6% (12/68) of participants
- Further EIK1003 Cohort 1D and EIK1004 docetaxel combination results are expected in the second half of 2027
The filing
Written by AI on Nov 9, 2026, 11:44 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on October 23, 2026.
Briefs are written by AI from the filing text and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the AI's reading of the filing for shareholders, not a price forecast. Not investment advice.