Evommune says EVO301 met Phase 2a primary endpoint in atopic dermatitis trial
Evommune presented late-breaking Phase 2a proof-of-concept data for its experimental drug EVO301 in moderate-to-severe atopic dermatitis at a European dermatology congress. The company said the drug met the trial's primary endpoint and plans to start a Phase 2b dose-ranging trial in mid-2027, a step that will take more time and money before any approval is possible.
Key points
- Week 12 EASI reduction was 55% for EVO301 versus 22% on placebo (p<0.01), in a 70-patient trial
- Treatment-related adverse events occurred in 10.4% of EVO301 patients versus 13.6% on placebo
- Company plans to initiate a subcutaneous Phase 2b dose-ranging trial in mid-2027
The filing
Written by AI on Nov 9, 2026, 11:46 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on October 01, 2026.
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