Exelixis Q2 revenue falls to $568.3 million; GAAP EPS $0.65 vs. $0.77 a year earlier
Exelixis reported second-quarter 2025 total revenues of $568.3 million, down from $637.2 million a year earlier, and GAAP diluted EPS of $0.65, down from $0.77. Net product revenues rose to $520.0 million from $437.6 million, but the prior-year quarter included a $150.0 million commercial milestone that lifted collaboration revenue. The company maintained its full-year 2025 financial guidance.
Key points
- Total revenues were $568.3 million versus $637.2 million in Q2 2024; collaboration revenues fell to $48.2 million from $199.6 million.
- Net product revenues rose to $520.0 million from $437.6 million, mainly due to higher sales volume.
- GAAP diluted EPS was $0.65 versus $0.77; non-GAAP diluted EPS was $0.75 versus $0.84.
- Full-year 2025 total revenue guidance of $2.25 billion to $2.35 billion was maintained.
The filing
Written by AI (Anthropic Claude, claude-haiku-5-5) on Nov 8, 2026, 1:11 AM ET, from the text of the filing and its press-release exhibits only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on July 28, 2025.
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