Korro Bio doses first cohort in Phase 1/2 ANCHOR trial of KRRO-121
Korro Bio said it has dosed the first cohort of participants in the ANCHOR Phase 1/2 clinical trial of KRRO-121, a treatment in development for hyperammonemia in urea cycle disorders and hepatic encephalopathy. The filing describes a clinical milestone in an early-stage program and contains no financial results, guidance, or changes to the company's financing or management.
Key points
- First cohort of healthy volunteers dosed with a single 2mg/kg dose in Australia
- Dosing of urea cycle disorder patients expected to start in the first half of 2027
- Interim readout expected in the second half of 2027
The filing
Written by AI on Nov 9, 2026, 8:53 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on October 05, 2026.
Briefs are written by AI from the filing text and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the AI's reading of the filing for shareholders, not a price forecast. Not investment advice.