Krystal Biotech Q4 revenue rises to $107.1 million; net income $51.4 million
Krystal Biotech reported fourth-quarter and full-year 2025 results, with product revenue from VYJUVEK rising from the prior-year periods. Net income for the quarter was $51.4 million, or $1.70 per diluted share, compared with $45.5 million, or $1.52 per diluted share, a year earlier. The company also issued fiscal 2026 non-GAAP R&D and SG&A expense guidance of $175.0 million to $195.0 million.
Key points
- Q4 2025 product revenue, net, was $107.1 million, up from $91.1 million in Q4 2024.
- Full-year 2025 product revenue, net, was $389.1 million, up from $290.5 million in 2024.
- Full-year 2025 net income was $204.8 million, or $6.84 per diluted share, versus $89.2 million, or $3.00 per diluted share, in 2024.
- FY 2026 non-GAAP R&D and SG&A expense guidance is $175.0 million to $195.0 million, excluding stock-based compensation.
The filing
Written by AI on Nov 8, 2026, 1:17 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on February 17, 2026.
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