Nektar reports 52-week rezpegaldesleukin data in alopecia areata and atopic dermatitis
Nektar Therapeutics presented long-term Phase 2b data for rezpegaldesleukin at the EADV 2026 congress, including off-treatment durability in alopecia areata. The filing also says a third Phase 3 atopic dermatitis study has started and a Phase 3 alopecia areata study is planned for early 2027. The filing reports clinical data only, with no revenue, earnings, or guidance figures.
Key points
- In alopecia areata, 75% (6 of 8) of patients maintained a SALT Score of 20 or less at 4 months off treatment, and 63% (5 of 8) at 6 months.
- SALT Score of 10 or less responses rose from 7% at the end of week 52 to 19% after 6 months off treatment.
- The Phase 3 ZENITH AA study in alopecia areata is planned to start in early 2027 with 850 patients.
- Management hosted a conference call and webcast at 8:00 a.m. ET on October 1, 2026.
The filing
Written by AI on Nov 9, 2026, 8:29 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on October 01, 2026.
Briefs are written by AI from the filing text and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the AI's reading of the filing for shareholders, not a price forecast. Not investment advice.