OnKure Therapeutics Q3 net loss widens to $17.8 million from $14.7 million
OnKure Therapeutics reported third quarter 2026 results with a net loss of $17.8 million, or $0.36 per share, compared with $14.7 million, or $1.09 per share, a year earlier. The dollar loss grew as research and development and general and administrative expenses rose, while the per-share loss narrowed on a much larger weighted share count of 49.9 million versus 13.5 million. The company reported $163.3 million in cash, cash equivalents and marketable securities as of September 30, 2026, and said this is expected to fund operations into 2029.
Key points
- Q3 2026 net loss was $17.8 million ($0.36 per share), up from $14.7 million ($1.09 per share) in Q3 2025
- R&D expenses were $15.1 million, up from $11.9 million; G&A expenses were $4.3 million, up from $3.6 million
- Cash, cash equivalents and marketable securities were $163.3 million at September 30, 2026, expected to provide runway into 2029
- IND submissions for OKI-355 (vascular anomalies) and OKI-345 (breast cancer) are planned for the first half of 2027
The filing
Written by AI on Nov 9, 2026, 8:53 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on November 04, 2026.
Briefs are written by AI from the filing text and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the AI's reading of the filing for shareholders, not a price forecast. Not investment advice.