Illumina cuts 2025 EPS outlook to $4.20-$4.30 on $85 million in tariff costs
Illumina reported first-quarter 2025 results, with core Illumina revenue of $1.04 billion, down 1% from a year earlier, and GAAP diluted EPS of $0.82 versus a loss of $0.79 in the prior-year period. The company lowered its full-year outlook, now expecting non-GAAP diluted EPS of $4.20-$4.30, down from about $4.50 in March, mainly due to tariffs. For shareholders, the guidance cut lowers expected earnings for 2025 even though the quarter's GAAP profit improved.
Key points
- Core Illumina Q1 2025 revenue was $1.04 billion, down 1% from Q1 2024 (flat on a constant currency basis).
- GAAP diluted EPS was $0.82 versus a loss of $0.79 a year earlier; non-GAAP diluted EPS was $0.97.
- 2025 non-GAAP diluted EPS guidance is $4.20-$4.30, down from about $4.50 in March, with $85 million in tariff-related costs cited.
- Core Illumina revenue is now expected to decline 1% to 3% on a constant currency basis in 2025, down from low single digit growth previously.
The filing
Written by AI on Nov 8, 2026, 1:30 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on May 08, 2025.
Briefs are written by AI from the filing text and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the AI's reading of the filing for shareholders, not a price forecast. Not investment advice.