Incyte Q4 2025 net product revenue up 20% to $1.22 billion; sets 2026 guidance
Incyte reported fourth quarter and full year 2025 results, with total revenue of $1.51 billion for the quarter and $5.14 billion for the year, and full year net product revenue of $4.35 billion, above its prior guidance of $4.23 to $4.32 billion. The company also gave 2026 total net product revenue guidance of $4.77 to $4.94 billion, and GAAP net income rose to $299.3 million in the quarter from $201.2 million a year earlier.
Key points
- Q4 2025 total revenue was $1.51 billion, up 28% year over year, including $100.0 million of milestone and contract revenue.
- Full year 2025 GAAP net income was $1.29 billion, compared with $32.6 million in 2024, and GAAP diluted EPS was $6.41 versus $0.15.
- Cash, cash equivalents and marketable securities were $3.6 billion at December 31, 2025, compared with $2.2 billion a year earlier.
The filing
Written by AI on Nov 8, 2026, 1:10 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on February 10, 2026.
Briefs are written by AI from the filing text and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the AI's reading of the filing for shareholders, not a price forecast. Not investment advice.