Xencor to receive $105 million from Alexion to settle Ultomiris U.S. royalty dispute
Xencor entered a settlement agreement with Alexion that resolves a dispute over U.S. royalties on Ultomiris, with Xencor to receive $105 million in two equal payments. Alexion will have no further obligation to pay royalties on U.S. sales, while ex-U.S. royalties are unchanged. Xencor said that, based on current operating plans, it expects cash to fund research and development programs and operations through 2028.
Key points
- Total payment of $105 million, in two $52.5 million installments
- First $52.5 million payment anticipated in August 2026; second payment due within 14 days after the one-year anniversary of the agreement
- Alexion has no further obligation to pay royalties on U.S. sales of Ultomiris; ex-U.S. royalties are unchanged
- Cash runway expected through 2028; year-end 2026 cash guidance to be updated with second-quarter 2026 results
The filing
Written by AI on Nov 8, 2026, 1:49 AM ET, from this filing only. Written later: this filing was briefed after the fact, when past filings were added to the site, so the brief may be read with hindsight; the filing itself is the record of what was known on July 29, 2026.
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