Alnylam Pharmaceuticals, Inc. (ALNY)

Nasdaq Health Care Biotechnology Nasdaq-100
$155.94
-0.72 (-0.46%)
Close of Nov 06, 2026 · end-of-day data
SMA 50SMA 2005Y/10Y use weekly candles (10/40-week averages)

Performance

price return
1W-5.5%
1M-30.6%
3M-28.1%
6M-47.1%
YTD-60.8%
1Y-64.1%
3Y-0.7%
5Y-2.3%

Key statistics

Full financials →
Market cap$20.9B
P/E (TTM)66.9
EPS (TTM, diluted)$2.33
P/S5.62
P/B5.80
EV / EBITDA35.5
Revenue (TTM)$3.71B
Revenue growth+65.2%
Net margin8.4%
ROE8.7%
Debt / equity0.19
FCF yield2.2%
Dividend yield—
Payout ratio—
Beta (1Y)0.47
Volatility (1Y)58.3%
52-week range$154.30 – $479.79
Avg volume (50D)2.00M

Revenue & net income — last 8 quarters

Statements →
Nov 5, 7:37 AM ET

Alnylam authorizes $1.0 billion buyback as Chief Commercialization Officer departs

Positive shareholder 5.028.01

Alnylam's board authorized a program to repurchase up to $1.0 billion of its common stock on November 2, 2026. The company also said Executive Vice President and Chief Commercialization Officer Tolga Tanguler will leave in December 2026, with a separation agreement still to be signed.

  • Board authorized a repurchase program of up to $1.0 billion of common stock on November 2, 2026.
  • The company anticipates repurchasing about $500 million by the end of 2026 and the balance during 2027.
  • The program has no expiration date and does not obligate the company to buy any particular amount; it may be modified, suspended or discontinued at any time.
  • Tolga Tanguler, Executive Vice President and Chief Commercialization Officer, will depart in December 2026; the terms of his departure are yet to be set in a written agreement.
Read the filing on SEC.gov ↗
Oct 29, 8:16 AM ET

Alnylam Q3 2026 revenue rises 17% to $1.46 billion; operating income falls 6%

Mixed earnings 2.02

Alnylam reported third quarter 2026 total revenues of $1.46 billion, up 17% from a year earlier, led by net product revenues of $1.29 billion, up 52%. GAAP net income reached $2.17 billion, or $15.72 per diluted share, but that figure includes a $1.9 billion income tax benefit, while GAAP income from operations fell 6% to $345.8 million. The company reiterated its full-year 2026 guidance.

  • Total revenues were $1,458.1 million versus $1,249.0 million in Q3 2025, up 17%.
  • Total net product revenues were $1,292 million, up 52%, with Total TTR net product revenues at $1,150 million.
  • GAAP income from operations was $345.8 million, down 6% from $368.0 million, while GAAP diluted EPS was $15.72 versus $2.14, helped by a $1.9 billion tax benefit.
  • Full-year 2026 total net product revenues guidance of $4,700 million to $5,100 million was reiterated.
Read the filing on SEC.gov ↗
Jul 30, 8:06 AM ET

Alnylam Q2 revenue rises 67% to $1.29 billion, but full-year TTR sales guidance is cut

Mixed guidance Written later 2.02

Alnylam reported second-quarter 2026 total revenues of $1.29 billion, up 67% from a year earlier, and GAAP net income of $164 million, compared with a net loss of $72 million in the prior-year quarter. The company lowered its full-year 2026 TTR net product revenue guidance to $4.2 billion to $4.5 billion from $4.4 billion to $4.7 billion, citing normalizing second-line demand for AMVUTTRA in the U.S.

  • Q2 2026 total revenues were $1,290.9 million, up 67% from $773.7 million in Q2 2025.
  • GAAP net income was $164.5 million, or $1.21 per diluted share, versus a loss of $0.55 per share a year earlier.
  • Full-year 2026 TTR net product revenue guidance was cut to $4,200 million to $4,500 million from $4,400 million to $4,700 million.
  • Full-year 2026 collaboration and royalty revenue guidance was raised to $575 million to $625 million from $400 million to $500 million.
Read the filing on SEC.gov ↗
May 27, 4:30 PM ET

Alnylam adds Benjamin Cravatt to board; stockholders re-elect three Class I directors

Neutral leadership Written later 5.025.07

Effective June 1, 2026, Alnylam expanded its board from ten to eleven members and elected Benjamin F. Cravatt, Ph.D. to fill the new seat. At its annual meeting, stockholders re-elected three Class I directors and approved executive pay in a non-binding vote, though one director's support was notably lower than the others.

  • Dr. Cravatt receives a $75,000 annual cash retainer and a stock option with a $600,000 grant date fair value.
  • Stuart A. Arbuckle, Yvonne L. Greenstreet, M.D., and Elliott Sigal, M.D., Ph.D. were re-elected as Class I directors to serve until the 2029 annual meeting.
  • Stockholders approved executive compensation with 111,772,389 votes for and 8,552,534 against.
  • PricewaterhouseCoopers LLP was ratified as independent auditor for fiscal 2026 with 119,847,735 votes for.
Read the filing on SEC.gov ↗

Briefs are written by AI from the filing text (each brief's own page names the model) and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the model's reading of the filing for shareholders, not a price forecast. Not investment advice.

Recent SEC filings

EDGAR ↗

Famous investors who own ALNY

All investors →
InvestorValue% of portfolioLast quarter
Ray Dalio Bridgewater Associates $29.98M0.12% Reduced

From each investor's latest 13F filing (Q2 2026); positions are as of the quarter end and filed up to 45 days later.

Trades disclosed by members of Congress

All ALNY congressional trades →
TradedMemberTypeAmount
May 12, 2025Jefferson Shreve IN-06Sell$15,001 – $50,000

From House periodic transaction reports (STOCK Act); amounts are the form's ranges.

Insider transactions

All insider trades →
DateInsiderTypeSharesPriceValue
Oct 02Supran Bryan
EVP, CLO and Secretary
Sell1.76K$226.88$398.86K

Prices are end-of-day and split-adjusted. Financial data from Alnylam Pharmaceuticals, Inc.'s SEC XBRL filings. Not investment advice.