PTC Therapeutics, Inc. (PTCT)

Nasdaq Health Care Pharmaceuticals S&P SmallCap 600
$65.44
-0.23 (-0.35%)
Close of Nov 06, 2026 · end-of-day data
SMA 50SMA 2005Y/10Y use weekly candles (10/40-week averages)

Performance

price return
1W+9.1%
1M+4.6%
3M-12.3%
6M-11.2%
YTD-13.8%
1Y-8.8%
3Y+254.7%
5Y+72.5%

Key statistics

Full financials →
Market cap$5.5B
P/E (TTM)—
EPS (TTM, diluted)$-1.40
P/S4.73
P/B—
EV / EBITDA26.6
Revenue (TTM)$1.16B
Revenue growth-35.1%
Net margin-9.2%
ROE—
Debt / equity—
FCF yield0.0%
Dividend yield—
Payout ratio—
Beta (1Y)0.82
Volatility (1Y)42.6%
52-week range$58.80 – $90.87
Avg volume (50D)1.17M

Revenue & net income — last 8 quarters

Statements →
Nov 3, 9:00 AM ET

PTC Therapeutics Board Authorizes Up to $500 Million Share Repurchase Program

Positive shareholder 7.018.01

PTC Therapeutics' Board of Directors authorized a share repurchase program allowing the company to buy back up to $500 million of its common stock, subject to market conditions. The filing does not give a timing or schedule for purchases, and the company says repurchases will be made at management's discretion and reported in its Form 10-Q and Form 10-K filings.

  • Authorization: up to $500 million of outstanding common stock, announced November 3, 2026
  • Repurchases may be made from time to time at management's discretion, subject to market conditions
  • Methods include open-market transactions with pre-set trading plans, privately negotiated deals, and accelerated share repurchases
  • CEO Matthew B. Klein said the program leaves financial flexibility to support existing programs and pursue potential business development transactions
Read the filing on SEC.gov ↗
Oct 29, 4:10 PM ET

PTC Therapeutics Q3 revenue rises to $358 million; raises product revenue guidance

Mixed earnings 2.027.01

PTC Therapeutics reported third-quarter 2026 total revenue of $358 million, up from $211.0 million a year earlier, and raised its full-year 2026 total and product revenue guidance. The company also recorded a net loss of $51.7 million, compared with net income of $15.9 million in the prior-year quarter, after a $111.0 million acquired in-process R&D charge for the ST-920 Fabry gene therapy.

  • Q3 2026 total revenue was $357.8 million, versus $211.0 million in Q3 2025; Sephience net product revenue was $181.9 million.
  • Net loss was $51.7 million ($0.62 per share) versus net income of $15.9 million a year earlier, including the $111.0 million ST-920 charge.
  • Full-year 2026 product revenue guidance was raised to $960 to $990 million from $850 to $950 million; total revenue guidance is $1.29 to $1.32 billion.
  • Cash, cash equivalents and marketable securities were $2,127.9 million on September 30, 2026.
Read the filing on SEC.gov ↗
Aug 28, 4:06 PM ET

PTC Therapeutics agrees to buy Sangamo's ST-920 Fabry gene therapy for $111 million upfront

Neutral m&a Written later 1.01

PTC Therapeutics entered an asset purchase agreement on August 25, 2026 to acquire ST-920, an AAV gene therapy candidate for Fabry disease, from bankrupt Sangamo Therapeutics. The deal carries a $111 million upfront payment plus up to $100 million in contingent milestones tied to FDA approval, and closing requires Bankruptcy Court approval, which is scheduled for a hearing on September 10, 2026.

  • Upfront payment of $111 million, plus up to $100 million in contingent milestones ($80 million on accelerated approval and $20 million on full approval)
  • Acquisition is subject to Bankruptcy Court approval (hearing scheduled September 10, 2026) and Hart-Scott-Rodino waiting period expiration
  • Either party may terminate if closing has not occurred by October 15, 2026, subject to specified exceptions
  • Representations and warranties do not survive closing and there is no indemnification for breaches
Read the filing on SEC.gov ↗
Jul 30, 4:05 PM ET

PTC Therapeutics Q2 revenue rises to $361 million; full-year product revenue guidance raised

Positive earnings Written later 2.025.027.01

PTC Therapeutics reported second-quarter 2026 total revenue of $360.5 million, up from $178.9 million a year earlier, and net income of $83.5 million, compared with a net loss of $64.8 million in the prior-year quarter. The company raised its 2026 product revenue guidance to $850 million to $950 million and its total revenue guidance to $1.18 billion to $1.28 billion, and it also appointed Hege Sollie-Zetlmayer, its former Chief Human Resources Officer, to the board.

  • Q2 2026 total revenue was $360.5 million, including $238.8 million of net product revenue and a $50.0 million Novartis milestone recorded as collaboration revenue.
  • Full-year 2026 product revenue guidance was raised to $850 million to $950 million from $750 million to $850 million.
  • Sephience generated $151.3 million in Q2 2026 net product revenue; cash, cash equivalents and marketable securities were $2.2 billion as of June 30, 2026.
  • Hege Sollie-Zetlmayer was appointed to the board effective July 28, 2026, filling a vacancy.
Read the filing on SEC.gov ↗

Briefs are written by AI from the filing text (each brief's own page names the model) and can contain mistakes — open the filing before acting on anything. Impact (1-5) and tone are the model's reading of the filing for shareholders, not a price forecast. Not investment advice.

Famous investors who own PTCT

All investors →
InvestorValue% of portfolioLast quarter
Renaissance Technologies $59.02M0.08% Added

From each investor's latest 13F filing (Q2 2026); positions are as of the quarter end and filed up to 45 days later.

Insider transactions

All insider trades →
DateInsiderTypeSharesPriceValue
Oct 14Schmertzler Michael
Director
Sell 10b5-12.50K$59.61$149.04K
Oct 09Boulding Mark Elliott
EXEC. VP AND CLO
Sell 10b5-1192$64.26$12.34K
Oct 07Schmertzler Michael
Director
Sell 10b5-12.50K$63.39$158.48K
Oct 06Boulding Mark Elliott
EXEC. VP AND CLO
Sell 10b5-12.07K$64.06$132.79K
Sep 30Steele Glenn Jr Md Phd
Director
Sell 10b5-112.00K$65.16$781.92K

Prices are end-of-day and split-adjusted. Financial data from PTC Therapeutics, Inc.'s SEC XBRL filings. Not investment advice.